Bone broth has been consumed across virtually every traditional culture for centuries — simmered bones yielding a rich, gelatinous stock prized for digestive support, joint health, and recovery. Modern nutrition research has examined these claims more rigorously, and the evidence is more nuanced than either enthusiastic advocates or sceptical dismissals suggest. Here is the 2025 evidence picture.
What Is Bone Broth?
Bone broth is made by simmering animal bones — beef, chicken, pork, or fish — for an extended period (typically 12–48 hours) with water, vegetables, and acid (vinegar). This long cooking time extracts collagen, gelatin, amino acids (particularly glycine, proline, and hydroxyproline), minerals (calcium, magnesium, phosphorus), and proteoglycans from the bone matrix and connective tissue. The result varies significantly in nutritional composition depending on the bones used, cooking time, acid added, and whether cartilage and connective tissue are included. This variability is one reason clinical research on bone broth specifically is difficult and limited.
Bone Broth Benefits: What the Evidence Shows
1. Collagen and Amino Acids — Ingredient-Level Evidence
The most honest assessment of bone broth’s benefits comes from understanding its ingredients rather than broth-level clinical trials. Bone broth contains collagen precursors (gelatin — hydrolysed collagen), glycine, proline, and hydroxyproline. These amino acids are well-evidenced for joint and skin health — but through collagen supplement research, not bone broth research directly. Cleveland Clinic (2025) notes that many broths may not provide enough collagen precursors to meaningfully boost the body’s collagen production, and that clinical benefits for skin or joints are better established for isolated collagen peptide supplements than for broth as a food. National Geographic’s 2025 science analysis reached the same conclusion: the evidence is indirect, built on ingredient plausibility rather than broth-specific trials.
2. Gut Health — Plausible but Unproven
Bone broth is frequently promoted for gut health, particularly leaky gut and intestinal permeability. The theoretical basis: gelatin coats the intestinal lining, glycine is anti-inflammatory in gut tissue, and glutamine (present in small amounts) is the primary fuel source for intestinal epithelial cells. Animal studies suggest possible anti-inflammatory effects in colitis models (PubMed 40180691, 2025). However, multiple authoritative sources including ZOE Nutrition, Cedars-Sinai, and Canadian Digestive Health Foundation explicitly state that human clinical evidence for bone broth’s gut-health benefits is limited and that gut-barrier claims remain unproven in people. For a better-evidenced gut-healing protocol, L-glutamine supplements, probiotics, and psyllium husk have significantly stronger clinical evidence than bone broth.
3. Joint Health — Better Evidence for Collagen Supplements
Bone broth is often recommended for joint pain because it contains collagen-related amino acids. However, multiple sources — including WebMD (2025) and Cedars-Sinai — state there is no solid scientific evidence that bone broth itself relieves joint pain or outperforms other protein sources for joints. The evidence for joint benefits belongs to collagen peptide supplements, which deliver standardised, concentrated amounts of the relevant amino acids in a form shown in clinical trials to improve osteoarthritis symptoms. Bone broth is an imprecise delivery vehicle for these compounds.
4. Mineral Content
Bone broth does contain minerals leached from bones during cooking — primarily calcium, magnesium, and phosphorus. However, multiple analyses show the mineral content is generally modest and variable. AARP notes that bone broth is “not a significant source of calcium” compared to dairy. The mineral contribution is real but should not be relied upon as a primary source.
5. Sleep and Anxiety — The Glycine Angle
This is perhaps bone broth’s most underappreciated potential benefit. Glycine — abundant in bone broth — is an inhibitory neurotransmitter with well-evidenced sleep-promoting and anxiolytic effects. RCTs show glycine supplementation before bed improves sleep quality and reduces next-day fatigue. Bone broth consumed in the evening provides a meaningful glycine dose in a food matrix, which may contribute to relaxation and sleep quality — though no trials have tested bone broth itself for sleep outcomes specifically.
Bone Broth vs Collagen Supplements: Which Is Better?
| Factor | Bone Broth | Collagen Peptide Supplements |
|---|---|---|
| Clinical evidence | Limited, indirect | Good — multiple RCTs |
| Collagen content | Variable, often low | Standardised, concentrated |
| Cost per serving | Low (homemade) to moderate | Moderate to high |
| Additional nutrients | Yes — minerals, electrolytes | No |
| Gut health support | Plausible via gelatin/glycine | Via glycine |
| Taste/palatability | High — satisfying whole food | Neutral — mixes into drinks |
How to Make Bone Broth at Home
- Bones: Use mixed bones with cartilage (knuckles, feet, necks) — cartilage provides the highest gelatin yield; marrow bones add richness
- Acid: Add 2 tablespoons of apple cider vinegar per litre of water — helps extract minerals and collagen from bones
- Time: Beef bones: 18–24 hours; chicken bones: 12–18 hours; fish bones: 4–6 hours
- Test: Good bone broth should gel when cooled — if it doesn’t, it lacks sufficient gelatin and cartilage was insufficient
- Quantity: 1–2 cups daily is the amount typically recommended by practitioners using bone broth therapeutically
Frequently Asked Questions
Bone broth provides collagen precursors (glycine, proline, hydroxyproline), gelatin, minerals, and electrolytes. Its plausible benefits include gut barrier support through gelatin and glycine, joint amino acid supply, sleep improvement via glycine’s inhibitory neurotransmitter effects, and general protein contribution. However, direct human clinical trials on bone broth itself are sparse — most evidence comes from studies on its component ingredients (particularly collagen peptides), which have stronger clinical backing.
Bone broth is plausibly beneficial for gut health through its gelatin (which coats the intestinal lining), glycine (anti-inflammatory), and small glutamine content. However, human clinical evidence specifically for bone broth and gut health is limited — gut-barrier claims remain unproven in clinical trials. For evidenced gut healing, L-glutamine supplements, probiotics, and prebiotic fibre have significantly stronger clinical data than bone broth, though bone broth as a warm, nourishing food is a reasonable complementary addition to a gut healing protocol.
Most recommendations are 1–2 cups (240–480ml) daily for general health benefits. There is no established therapeutic dose because clinical trials on bone broth specifically are lacking. As a food, it is safe to consume daily. Be aware that some commercial bone broths are high in sodium — check labels if you monitor salt intake. Homemade bone broth that gels when cooled provides more gelatin and is generally superior to commercial options.
This article is for informational purposes only. If you have specific health conditions, consult a healthcare provider or registered dietitian before using bone broth therapeutically.